ChemBioServer Info

Welcome to ChemBioServer

This Server hosts a group of tools and web services developed to provide advanced filtering, clustering and networking of chemical compounds facilitating both drug discovery and repurposing.

This Server provides the following services:
Uploading and Browsing Compounds in 2D and 3D.
Filtering of compounds based on physicochemical properties.
Substructure filtering of compounds based on custom sdf files.
Van der Waals filtering using distance and energy tests.
Toxicity filtering using specific organic toxic roots.
Hierarchical clustering with 4 different distances.
Affinity Propagation clustering, providing exemplars for each cluster.
Structural Similarity Network Visualization and Analysis.
Creating custom pipeline filtering.
Visualization of compounds' properties.


Please cite the program as:
ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery. Athanasiadis E., Cournia Z., Spyrou G. Bioinformatics. 2012 Nov 15;28(22):3002-3. Epub 2012 Sep 8. http://dx.doi.org/10.1093/bioinformatics/bts551