Filtering Rules

Step 1.
Please, Upload files* in either ".sdf", or ".mol" format.

*Warning:
‒ Uploaded filename should not contain special characters ^ ()_
‒ Files are temporary saved on the server and deleted after processing.
Maximum allowed upload size is 100MB .

The tested compounds must pass ALL of the following criteria:

Lipinski Rules
• Molecular Weight: < 500
• Hydrogen Bond Donors: 5
• Hydrogen Bond Acceptors: 10
• Partition coefficient log P 5

Veber Rules
• Polar surface Area 140 Å2
• Rotatable Bonds 10

Ghose Filters
• Total Atoms 20 AND 70
• Molar Refractivity 40 AND 130

Final Step.

Processing Data...
loading..
Please wait few minutes,
Do not Press Refress or Any Other Button,
Results will be displayed automatically.


*After the next successful execution your downloadable file links will be:

1. Compounds that Pass searching criteria: http://chembioserver.vi-seem.eu/upload/77Bci1aFHc_pass.sdf

2. Compounds that Fail searching criteria: http://chembioserver.vi-seem.eu/upload/77Bci1aFHc_fail.sdf

*Results are stored for a week.