Filtering Rules

• Step 1.
Please, Upload files* in either ".sdf", or ".mol" format.

*Warning:
‒ Uploaded filename should not contain special characters ^ ()_
‒ Files are temporary saved on the server and deleted after processing.
‒ Maximum allowed upload size is 100MB .

The tested compounds must pass ALL of the following criteria:

Lipinski Rules
• Molecular Weight: < 500
• Hydrogen Bond Donors: ≤ 5
• Hydrogen Bond Acceptors: ≤ 10
• Partition coefficient log P ≤ 5

Veber Rules
• Polar surface Area ≤ 140 Å2
• Rotatable Bonds ≤ 10

Ghose Filters
• Total Atoms ≥ 20 AND ≤ 70
• Molar Refractivity ≥ 40 AND ≤ 130

• Final Step.

Processing Data...
loading..
Please wait few minutes,
Do not Press Refress or Any Other Button,
Results will be displayed automatically.


*After the next successful execution your downloadable file links will be:

1. Compounds that Pass searching criteria: http://chembioserver.vi-seem.eu/upload/kNOogBm01A_pass.sdf

2. Compounds that Fail searching criteria: http://chembioserver.vi-seem.eu/upload/kNOogBm01A_fail.sdf

*Results are stored for a week.


Launched on Dec 30th, 2011 Updated on Sep 27th, 2019